SCHEMBL30050877

SCHEMBL30050877

CSCC[C@H](NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.60
▸ FNTA P49354 6/20 0.53
▸ FNTB P49356 6/20 0.53
▸ PGGT1B P53609 6/20 0.53
▸ MME P08473 1/20 0.53
▸ ANPEP P15144 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051473 0.95 LTA4H (0.64) LTA4HFNTAFNTBPGGT1B
SCHEMBL31501129 0.90 LTA4H (0.51) LTA4HFNTAFNTBPGGT1B
SCHEMBL11225559 0.89 LTA4H (0.54) LTA4H
SCHEMBL5507650 0.88 LTA4H (0.58) LTA4HFNTAFNTBPGGT1B
SCHEMBL30052344 0.87 LTA4H (0.58) LTA4HFNTAFNTBPGGT1BMME
SCHEMBL30050929 0.87 FNTA (0.59) LTA4HFNTAFNTBPGGT1BMME
SCHEMBL30051757 0.87 FNTA (0.59) LTA4HFNTAFNTBPGGT1BMME
SCHEMBL31741305 0.87 BACE1 (0.51) LTA4HFNTAFNTB
SCHEMBL8836882 0.86 GNPAT (0.61) LTA4HFNTAFNTBPGGT1BMME
SCHEMBL8068319 0.86 MME (0.61) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP LTA4H 3533/4885FNTA 734/4885FNTB 479/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD LTA4H 1299/4885FNTA 776/4885FNTB 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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