Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 9/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931425 | 1.00 | ADRA2A (0.51) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL2484239 | 0.81 | EPHX1 (0.60) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL12257241 | 0.80 | ADRA2A (0.54) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL17315551 | 0.79 | IP6K1 (0.64) | SMN1; SMN2 | |
| SCHEMBL24819761 | 0.79 | ADRA2A (0.47) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL6625320 | 0.78 | ADRA2A (0.58) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL24819763 | 0.77 | EPHX1 (0.46) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL2541647 | 0.76 | ADRA2A (0.50) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL2536231 | 0.76 | QPCT (0.67) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL5063947 | 0.74 | ADRA2A (0.58) | ADRA2AADRA2CADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346562-A1 | OCT4 HIGH-SELECTIVITY ACTIVATOR | IREGENE THERAPEUTICS LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| CN-115572285-B | OCT4 high-selectivity activator | 武汉睿健医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| EP-4361131-A1 | OCT4 HIGH-SELECTIVITY ACTIVATOR | Iregene Therapeutics Ltd (CN) | 2024-05-01 | — | — | EP | disclosed |
| CN-115572256-A | OCT4 high selectivity activator | 武汉睿健医药科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-115572285-A | OCT4 high selectivity activator | 武汉睿健医药科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| WO-2022266794-A1 | OCT4 HIGH-SELECTIVITY ACTIVATOR | 武汉睿健医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346562-A1 | OCT4 HIGH-SELECTIVITY ACTIVATOR | POU2F1, POU5F1, POU2F2 | ADRA2A 149/4885ADRA2C 822/4885ADRA1D 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.