SCHEMBL30051363

SCHEMBL30051363

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nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
ALDH1A1 P00352 2/20 0.42
ENPEP Q07075 9/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
PLA2G2A P14555 1/20 0.38
PLA2G5 P39877 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CTSD P07339 2/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4658537 0.94 ALDH1A1 (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL29641579 0.94 ALDH1A1 (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL4658535 0.94 ALDH1A1 (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL29562926 0.94 ALDH1A1 (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL7619811 0.94 ALDH1A1 (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL31438647 0.94 ALDH1A1 (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL29906310 0.92 ALDH1A1 (0.51) MMEACECPA1ACE2ALDH1A1
SCHEMBL29353917 0.92 ALDH1A1 (0.51) MMEACECPA1ACE2ALDH1A1
SCHEMBL30051813 0.90 ALDH1A1 (0.45) MMEACECPA1ACE2ALDH1A1
SCHEMBL30051417 0.89 ALDH1A1 (0.47) ALDH1A1ENPEPL3MBTL1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
CN-116496962-A Pseudo uridine engineering bacterium, application thereof and method for producing pseudo uridine 台州学院 2023-07-28 CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP MME 824/4885ACE 1190/4885CPA1 245/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD MME 105/4885ACE 486/4885CPA1 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.