SCHEMBL30051389

SCHEMBL30051389

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nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 7/20 0.46
▸ FNTB P49356 7/20 0.46
▸ ENPEP Q07075 7/20 0.45
▸ ALDH1A1 P00352 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CTSD P07339 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051213 0.95 FNTA (0.44) FNTAFNTBENPEPALDH1A1CTSD
SCHEMBL30051191 0.95 ENPEP (0.47) ENPEPALDH1A1L3MBTL1
SCHEMBL13154778 0.95 ENPEP (0.49) FNTAFNTBENPEPALDH1A1L3MBTL1
SCHEMBL14941274 0.95 ENPEP (0.49) FNTAFNTBENPEPALDH1A1L3MBTL1
SCHEMBL14941273 0.95 ENPEP (0.49) FNTAFNTBENPEPALDH1A1L3MBTL1
SCHEMBL17880750 0.90 FNTA (0.50) FNTAFNTBALDH1A1
SCHEMBL30052545 0.90 FNTA (0.50) FNTAFNTBALDH1A1
SCHEMBL30051938 0.90 ENPEP (0.45) FNTAFNTBENPEPALDH1A1L3MBTL1
SCHEMBL30051929 0.88 ENPEP (0.44) FNTAFNTBENPEPALDH1A1L3MBTL1
SCHEMBL11668382 0.87 FNTA (0.47) FNTAFNTBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP FNTA 734/4885FNTB 479/4885ENPEP 18/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD FNTA 776/4885FNTB 452/4885ENPEP 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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