SCHEMBL30051395

SCHEMBL30051395

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP3 Q9NY33 5/20 0.59
DPP4 P27487 1/20 0.56
OPRM1 P35372 1/20 0.52
KRAS P01116 1/20 0.51
SOS1 Q07889 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30052289 0.97 DPP3 (0.59) DPP3DPP4
SCHEMBL30051339 0.96 DPP4 (0.58) DPP3DPP4KRASSOS1
SCHEMBL29666786 0.95 DPP3 (0.59) DPP3DPP4OPRM1
SCHEMBL30432327 0.92 DPP3 (0.55) DPP3
SCHEMBL30311085 0.91 DPP4 (0.56) DPP3DPP4KRASSOS1
SCHEMBL31475666 0.90 CCKBR (0.54) DPP3
SCHEMBL29829082 0.90 DPP4 (0.54) DPP3DPP4KRASSOS1
SCHEMBL30051839 0.90 DPP4 (0.54) DPP3DPP4KRASSOS1
SCHEMBL29966903 0.90 DPP4 (0.54) DPP3DPP4
SCHEMBL30311056 0.88 DPP3 (0.52) DPP3DPP4OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
CN-121758548-A Bioactive peptide in low-grade tobacco leaves, screening preparation and application thereof 云南省烟草公司玉溪市公司 2026-03-31 CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP DPP3 25/4885DPP4 43/4885OPRM1 804/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD DPP3 64/4885DPP4 73/4885OPRM1 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.