Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.62 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30915103 | 1.00 | GNPAT (0.62) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL1711598 | 0.99 | GNPAT (0.63) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL1711765 | 0.99 | GNPAT (0.63) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL1711769 | 0.99 | GNPAT (0.63) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL1711591 | 0.99 | GNPAT (0.63) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL29540649 | 0.99 | GNPAT (0.63) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL7120877 | 0.97 | ERAP2 (0.62) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL29630365 | 0.97 | ERAP2 (0.62) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL30463392 | 0.96 | ERAP2 (0.59) | GNPATERAP2LNPEPOPRK1MMP2 | |
| SCHEMBL29883922 | 0.96 | ERAP2 (0.59) | GNPATERAP2LNPEPOPRK1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | BRANDEIS UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | PEPD, PAM, VIP | GNPAT 1084/4885ERAP2 831/4885LNPEP 13/4885 |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | GNPAT 1048/4885ERAP2 87/4885LNPEP 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.