SCHEMBL7120877

SCHEMBL7120877

NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 3/20 0.62
LNPEP Q9UIQ6 3/20 0.62
MMP2 P08253 1/20 0.58
GNPAT O15228 1/20 0.58
OPRK1 P41145 1/20 0.54
ECE1 P42892 1/20 0.53
ERAP1 Q9NZ08 1/20 0.51
CTSC P53634 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630365 1.00 ERAP2 (0.62) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL30915103 0.97 GNPAT (0.62) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL30051985 0.97 GNPAT (0.62) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL29372662 0.97 ERAP2 (0.65) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL29382413 0.97 ERAP2 (0.65) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL9747671 0.97 ERAP2 (0.65) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL1711485 0.97 ERAP2 (0.65) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL28540087 0.97 ERAP2 (0.65) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL170652 0.97 ERAP2 (0.65) ERAP2LNPEPMMP2GNPATOPRK1
SCHEMBL30463392 0.96 ERAP2 (0.59) ERAP2LNPEPMMP2GNPATOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080883-A Antibacterial peptide and application thereof 合肥科生景肽生物科技有限公司 2024-12-06 CN claimed
US-20220062371-A1 LIGAND-DRUG-CONJUGATES AS SUBSTRATES FOR SELECTIVE CLEAVAGE BY THE EXOPEPTIDASE ACTIVITY OF CATHEPSIN B DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2022-03-03 US claimed
US-20250249113-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES DEBIOPHARM RESEARCH & MANUFACTURING SA (CH) 2025-08-07 US disclosed
CN-119255824-A Ligand-drug conjugates with improved pharmacokinetic and drug release profiles 德比欧药物研究有限公司 2025-01-03 CN disclosed
CN-119080883-A Antibacterial peptide and application thereof 合肥科生景肽生物科技有限公司 2024-12-06 CN disclosed
US-20220062371-A1 LIGAND-DRUG-CONJUGATES AS SUBSTRATES FOR SELECTIVE CLEAVAGE BY THE EXOPEPTIDASE ACTIVITY OF CATHEPSIN B DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2022-03-03 US disclosed
EP-1358342-A2 RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM The Children's Medical Center Corporation (US) 2003-11-05 EP disclosed
WO-2002059338-A2 RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2002-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220062371-A1 LIGAND-DRUG-CONJUGATES AS SUBSTRATES FOR SELECTIVE CLEAVAGE BY THE EXOPEPTIDASE ACTIVITY OF CATHEPSIN B CTSB, CTSE, CTSV ERAP2 46/4885LNPEP 13/4885MMP2 116/4885
US-20250249113-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES FCER2, FCGR2A, FCGR1A ERAP2 830/4885LNPEP 150/4885MMP2 2635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.