Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | BRD4 | O60885 | 7/20 | 0.60 |
| ▸ | BRD2 | P25440 | 1/20 | 0.60 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.60 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.60 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.60 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.60 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | IL17A | Q16552 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348420 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL378252 | 0.96 | KDM4E (0.61) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL30053496 | 0.90 | BRD4 (0.58) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL378020 | 0.90 | BRD4 (0.58) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL348652 | 0.90 | BRD4 (0.58) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL30052318 | 0.89 | BRD4 (0.55) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL377720 | 0.89 | BRD4 (0.55) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL378038 | 0.89 | BRD4 (0.55) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL377629 | 0.88 | BRD4 (0.62) | KDM4EALDH1A1MAPTBRD4BRD2 | |
| SCHEMBL377547 | 0.88 | BRD4 (0.59) | KDM4EALDH1A1MAPTBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984016-A | Compositions and methods for treating complement-associated diseases | 雷斯韦洛吉克斯公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114984016-A | Compositions and methods for treating complement-associated diseases | 雷斯韦洛吉克斯公司 | 2022-09-02 | — | — | CN | disclosed |