SCHEMBL378252

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL348420	0.96	KDM4E (0.65)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL30053201	0.96	KDM4E (0.65)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL30458677	0.88	BRD4 (0.56)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL378514	0.87	BRD4 (0.56)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL377771	0.86	BRD4 (0.55)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL30053496	0.86	BRD4 (0.58)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL378020	0.86	BRD4 (0.58)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL348652	0.86	BRD4 (0.58)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL30052318	0.85	BRD4 (0.55)	KDM4EALDH1A1MAPTBRD4BRD2
	SCHEMBL377720	0.85	BRD4 (0.55)	KDM4EALDH1A1MAPTBRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.