Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ATF4 | P18848 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24997979 | 1.00 | CASP3 (0.46) | CASP3SENP8SENP7SENP6CNR2 | |
| SCHEMBL24997974 | 0.87 | CASP3 (0.49) | CASP3SENP8SENP7SENP6CNR2 | |
| SCHEMBL30053014 | 0.87 | CASP3 (0.49) | CASP3SENP8SENP7SENP6CNR2 | |
| SCHEMBL24997967 | 0.84 | SMN1; SMN2 (0.39) | CNR2MAPTATF4POLBLMNA | |
| SCHEMBL24997261 | 0.84 | ATF4 (0.43) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL30053354 | 0.84 | ATF4 (0.43) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL24997943 | 0.83 | NPY5R (0.49) | NPY5RATF4USP30 | |
| SCHEMBL24997274 | 0.83 | ATF4 (0.43) | NPY5RMAPTKMT2AATF4POLB | |
| SCHEMBL24997277 | 0.80 | CASP3 (0.56) | CASP3SENP8SENP7SENP6CNR2 | |
| SCHEMBL24998170 | 0.78 | ATF4 (0.58) | CASP3SENP8SENP7SENP6ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256609-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-12-08 | — | — | WO | disclosed |