Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADK | P55263 | 10/20 | 0.49 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23834528 | 1.00 | HASPIN (0.52) | HASPINSRCMTORRAB9AADK | |
| SCHEMBL16237288 | 0.89 | SRC (0.59) | SRCMTORRAB9AADKABL1 | |
| SCHEMBL23703132 | 0.88 | MTOR (0.54) | HASPINSRCMTORRAB9AADK | |
| SCHEMBL23703131 | 0.88 | MTOR (0.54) | HASPINSRCMTORRAB9AADK | |
| SCHEMBL1933267 | 0.84 | RIPK2 (0.63) | SRCMTORRAB9AADKABL1 | |
| SCHEMBL1933264 | 0.84 | RIPK2 (0.63) | SRCMTORRAB9AADKABL1 | |
| SCHEMBL1940882 | 0.84 | ABL1 (0.64) | SRCMTORRAB9AADKABL1 | |
| SCHEMBL30155310 | 0.84 | ABL1 (0.64) | SRCMTORRAB9AADKABL1 | |
| SCHEMBL400626 | 0.84 | SRC (0.61) | SRCMTORRAB9AADKABL1 | |
| SCHEMBL29484468 | 0.84 | SRC (0.61) | SRCMTORRAB9AADKABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298180-B | Compounds for treating or inhibiting recurrence of acute myeloid leukemia | 日本理化学研究所 | 2025-06-10 | — | — | CN | disclosed |
| EP-4121430-A1 | COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA | Flash Therapeuttics, LLC (US) | 2023-01-25 | — | — | EP | disclosed |
| CN-115298180-A | Compounds for treating or inhibiting recurrence of acute myeloid leukemia | 富雷旭医疗有限责任公司 | 2022-11-04 | — | — | CN | disclosed |