Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thioglycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioglycolic Acid SCHEMBL10489543 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL60562 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL538077 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL331393 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL99587 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL6679887 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL2720474 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL538389 | 0.92 | ENPEP (0.33) | LMNAANPEPENPEPTSHRFOLH1 | |
| Thioglycolic Acid SCHEMBL31042705 | 0.89 | ENPEP (0.32) | LMNAANPEPENPEPTSHRFOLH1 | |
| Glycolic Acid SCHEMBL27550333 | 0.86 | ALDH1A1 (0.32) | ANPEPENPEPTSHRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118973822-A | Lithographic printing plate precursor | 易客发有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-117715759-A | Lithographic printing plate precursor | 易客发有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-116745130-A | Lithographic printing plate precursor | 爱克发胶印有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115243896-A | Lithographic printing plate precursor | 爱克发胶印有限公司 | 2022-10-25 | — | — | CN | disclosed |