Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.37 |
| ▸ | UBA3 | Q8TBC4 | 3/20 | 0.37 |
| ▸ | UBA6 | A0AVT1 | 2/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | NEDD8 | Q15843 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23274005 | 1.00 | METTL3 (0.46) | METTL3CA2PRMT5WDR77NAE1 | |
| SCHEMBL29772295 | 0.87 | METTL3 (0.48) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29772294 | 0.87 | METTL3 (0.48) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL23313008 | 0.87 | METTL3 (0.48) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29772274 | 0.84 | METTL3 (0.47) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL25015554 | 0.84 | METTL3 (0.47) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL25015921 | 0.81 | METTL3 (0.72) | METTL3PRMT5WDR77 | |
| SCHEMBL30060440 | 0.81 | METTL3 (0.42) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL30058699 | 0.79 | METTL3 (0.41) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL25016861 | 0.77 | METTL3 (0.39) | METTL3PRMT5WDR77CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298179-A | METTL3 modulators | 埃克森特治疗公司 | 2022-11-04 | — | — | CN | disclosed |