Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | LPL | P06858 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24685618 | 0.86 | AAK1 (0.37) | ROCK1LIPGLPLF11F2 | |
| SCHEMBL30058336 | 0.86 | AAK1 (0.37) | ROCK1LIPGLPLF11F2 | |
| SCHEMBL30059622 | 0.84 | ROCK1 (0.33) | ROCK1LIPGLPLF11F2 | |
| SCHEMBL24685032 | 0.83 | HIF1A (0.36) | ROCK1LIPGLPLBACE1F11 | |
| SCHEMBL6454343 | 0.78 | CYP3A4 (0.42) | CYP3A4 | |
| SCHEMBL2558324 | 0.75 | ROCK1 (0.43) | ROCK1LIPGLPLBACE1BACE2 | |
| SCHEMBL17423909 | 0.73 | ROCK1 (0.45) | ROCK1LIPGLPLBACE1BACE2 | |
| SCHEMBL2548581 | 0.73 | ROCK1 (0.41) | ROCK1LIPGLPLBACE1BACE2 | |
| SCHEMBL13718426 | 0.72 | LPL (0.49) | ROCK1LIPGLPLBACE1BACE2 | |
| SCHEMBL28981113 | 0.71 | CNR2 (0.47) | ROCK1HIF1ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337639-A1 | NAMPT INHIBITORS AND USES THEREOF | Remedy Plan, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022241257-A1 | NAMPT INHBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2022-11-17 | — | — | WO | disclosed |