Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058336 | 0.84 | AAK1 (0.37) | ROCK1HIF1ALIPGLPLF11 | |
| SCHEMBL30057793 | 0.84 | ROCK1 (0.43) | ROCK1HIF1ALIPGLPLF11 | |
| SCHEMBL24685618 | 0.84 | AAK1 (0.37) | ROCK1HIF1ALIPGLPLF11 | |
| SCHEMBL24685032 | 0.80 | HIF1A (0.36) | ROCK1HIF1ALIPGLPLF11 | |
| SCHEMBL24976747 | 0.79 | FSCN1 (0.35) | ROCK1HIF1AESR2LIPGLPL | |
| SCHEMBL2427133 | 0.71 | ESR2 (0.38) | ROCK1HIF1AESR2LIPGLPL | |
| SCHEMBL14764058 | 0.71 | XDH (0.41) | — | |
| SCHEMBL18339643 | 0.71 | ESR2 (0.33) | ESR2LIPGLPL | |
| SCHEMBL28576949 | 0.69 | HIF1A (0.40) | ROCK1HIF1AESR2LIPGLPL | |
| SCHEMBL14771879 | 0.69 | XDH (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337639-A1 | NAMPT INHIBITORS AND USES THEREOF | Remedy Plan, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022241257-A1 | NAMPT INHBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2022-11-17 | — | — | WO | disclosed |