Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23875548 | 1.00 | PKM (0.61) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL23609038 | 0.80 | SMN1; SMN2 (0.66) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29975347 | 0.80 | SMN1; SMN2 (0.66) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL25282915 | 0.79 | PKM (0.83) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL30058100 | 0.79 | PKM (0.83) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL23875450 | 0.77 | PKM (0.54) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13246375 | 0.77 | SMN1; SMN2 (0.77) | PKMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL20214357 | 0.75 | TDP1 (0.50) | ALDH1A1SMN1; SMN2MAPTKDM4ETSHR | |
| SCHEMBL1341908 | 0.71 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL5655457 | 0.71 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335046-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-11-11 | — | — | CN | disclosed |