Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16145641 | 0.85 | ACHE (0.53) | ACHEEPHX1 | |
| SCHEMBL16145948 | 0.83 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL13387497 | 0.81 | ACHE (0.49) | ACHEEPHX1 | |
| SCHEMBL14469954 | 0.79 | ACHE (0.47) | ACHE | |
| SCHEMBL8258529 | 0.79 | ACHE (0.47) | ACHE | |
| SCHEMBL10794458 | 0.79 | ACHE (0.59) | ACHEEPHX1 | |
| SCHEMBL29696546 | 0.78 | ACHE (0.46) | ACHE | |
| SCHEMBL7051358 | 0.78 | GNAI3 (0.49) | ACHE | |
| SCHEMBL30849236 | 0.78 | ACHE (0.46) | ACHE | |
| SCHEMBL8389807 | 0.78 | ACHE (0.50) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077283-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-10-26 | — | — | EP | disclosed |