Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649726 | 0.81 | CCNC (0.42) | MAP4K1MAP4K3IRAK4CCNCCDK8 | |
| SCHEMBL21013530 | 0.74 | POLB (0.46) | ALDH1A1CYP3A4KCNH2 | |
| SCHEMBL29606664 | 0.74 | POLB (0.46) | ALDH1A1CYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL30504137 | 0.73 | POLB (0.45) | ALDH1A1CYP3A4KCNH2 | |
| SCHEMBL30057264 | 0.70 | ALDH1A1 (0.44) | MAP4K1ALDH1A1FGFR1 | |
| SCHEMBL22574413 | 0.70 | PDK2 (0.40) | ALDH1A1CYP3A4 | |
| SCHEMBL6062278 | 0.69 | MAOA (0.41) | CCNCCDK8HASPINPSMB1 | |
| SCHEMBL6742481 | 0.69 | MEN1 (0.54) | ALDH1A1CYP3A4KCNH2 | |
| SCHEMBL4649734 | 0.69 | CNR2 (0.39) | PIK3CBSRCCYP3A4 | |
| SCHEMBL9089041 | 0.67 | NPSR1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |