Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245551 | 1.00 | ATM (0.47) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL25784400 | 0.84 | TDP1 (0.46) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL3010413 | 0.83 | ATM (0.51) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL3396060 | 0.81 | CYP1A2 (0.55) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL23200508 | 0.80 | ATM (0.51) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL10473975 | 0.80 | MAPT (0.50) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL13262511 | 0.80 | ATM (0.55) | ATMTDP1SNCAALDH1A1MAPT | |
| SCHEMBL1028874 | 0.79 | PDGFRB (0.56) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL11630295 | 0.79 | NPC1 (0.56) | ATMTDP1SNCAKMT2AALDH1A1 | |
| SCHEMBL3804806 | 0.78 | KMT2A (0.60) | KMT2AALDH1A1SIGMAR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335046-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-11-11 | — | — | CN | disclosed |