Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP10 | Q14694 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994232 | 0.87 | CYP1A2 (0.50) | ATMTDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL30410464 | 0.87 | CYP1A2 (0.50) | ATMTDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL3396060 | 0.85 | CYP1A2 (0.55) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL26803674 | 0.84 | ATM (0.49) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL23200508 | 0.84 | ATM (0.51) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL1028874 | 0.83 | PDGFRB (0.56) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL30059615 | 0.83 | ATM (0.47) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL25245551 | 0.83 | ATM (0.47) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL29805390 | 0.83 | MTNR1A (0.46) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL11630295 | 0.83 | NPC1 (0.56) | ATMTDP1SNCAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197938-A1 | Process for producing indole compoud | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20070083053-A1 | Process for producing indole compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197938-A1 | Process for producing indole compoud | IDO1, IDO2, NOS2 | ATM 2683/4885TDP1 3383/4885SNCA 821/4885 |
| US-20070083053-A1 | Process for producing indole compound | IDO2, IDO1, TDO2 | ATM 2602/4885TDP1 3755/4885SNCA 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.