Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594106 | 0.87 | CYP1A2 (0.50) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL3396060 | 0.85 | CYP1A2 (0.55) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL3010413 | 0.84 | ATM (0.51) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL11630295 | 0.83 | NPC1 (0.56) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL4101251 | 0.82 | CA2 (0.43) | SNCAMAPTALDH1A1CYP1A2KDM4E | |
| SCHEMBL10615900 | 0.82 | BACE1 (0.49) | SNCAMAPTALDH1A1MAPK1CYP1A2 | |
| SCHEMBL10509627 | 0.81 | TDP1 (0.51) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL25407643 | 0.81 | MEN1 (0.46) | MAPTALDH1A1MAPK1CYP1A2KMT2A | |
| SCHEMBL10509624 | 0.81 | TDP1 (0.51) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL30599924 | 0.81 | MEN1 (0.46) | MAPTALDH1A1MAPK1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805214-B1 | JAK3 SELECTIVE INHIBITOR | UNIV PEKING SHENZHEN GRADUATE SCHOOL (CN) | 2023-07-05 | — | — | EP | disclosed |
| US-11578060-B2 | JAK3 selective inhibitor | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2023-02-14 | — | — | US | disclosed |
| CN-110551103-B | JAK3 selective inhibitor | 北京大学深圳研究生院 | 2022-08-23 | — | — | CN | disclosed |
| US-20210214344-A1 | JAK3 SELECTIVE INHIBITOR | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2021-07-15 | — | — | US | disclosed |
| EP-3805214-A1 | JAK3 SELECTIVE INHIBITOR | Peking University Shenzhen Graduate School (CN) | 2021-04-14 | — | — | EP | disclosed |
| CN-110551103-A | JAK3 selective inhibitor | SHENZHEN GRADUATE SCHOOL PEKING UNIV | 2019-12-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214344-A1 | JAK3 SELECTIVE INHIBITOR | JAK3, JAK1, JAK2 | ATM 1152/4885TDP1 4414/4885SNCA 4279/4885 |
| US-11578060-B2 | JAK3 selective inhibitor | JAK3, JAK1, JAK2 | ATM 1152/4885TDP1 4414/4885SNCA 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.