Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.40 |
| ▸ | GABRD | O14764 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.40 |
| ▸ | GABRE | P78334 | 3/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241721 | 1.00 | KDM4E (0.43) | KDM4EGAAGABRPGABRDGABRA1 | |
| SCHEMBL25788805 | 0.82 | KDM4E (0.45) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25788808 | 0.81 | HTR7 (0.42) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25241406 | 0.79 | KMT2A (0.40) | KDM4EGAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL23875565 | 0.78 | KDM4E (0.47) | KDM4EGAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL25783942 | 0.78 | CHRNB2 (0.46) | KDM4ECHRNB2CHRNA4IMPDH2ALDH1A1 | |
| SCHEMBL23875612 | 0.77 | KDM4E (0.48) | KDM4EGAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL30227291 | 0.77 | KDM4E (0.48) | KDM4EGAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL30227222 | 0.73 | CHRNB2 (0.51) | KDM4EGAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL23875541 | 0.73 | CHRNB2 (0.51) | KDM4EGAAKMT2ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335046-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-11-11 | — | — | CN | disclosed |