Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21090678 | 1.00 | ABCG2 (0.46) | ABCG2NPSR1AKR1C3AKR1C2ABCB1 | |
| SCHEMBL21090661 | 0.90 | NPSR1 (0.52) | ABCG2NPSR1AKR1C3AKR1C2MAPT | |
| SCHEMBL30063461 | 0.90 | NPSR1 (0.52) | ABCG2NPSR1AKR1C3AKR1C2MAPT | |
| SCHEMBL25791037 | 0.89 | MAPK14 (0.39) | ABCG2NPSR1AKR1C3AKR1C2MLYCD | |
| SCHEMBL21054644 | 0.89 | ABCG2 (0.46) | ABCG2AKR1C3AKR1C2ABCB1MAPK14 | |
| SCHEMBL30061322 | 0.87 | HPGD (0.41) | ABCG2MAPK14MAPTHPGD | |
| SCHEMBL21054146 | 0.87 | HPGD (0.41) | ABCG2MAPK14MAPTHPGD | |
| SCHEMBL21055838 | 0.87 | ABCG2 (0.48) | ABCG2AKR1C3AKR1C2ABCB1MAPK14 | |
| SCHEMBL30062650 | 0.87 | ABCG2 (0.48) | ABCG2AKR1C3AKR1C2ABCB1MAPK14 | |
| SCHEMBL21054627 | 0.87 | AKR1C3 (0.51) | ABCG2AKR1C3AKR1C2ABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524943-B1 | Benzocarbonyl compounds | VIVACE THERAPEUTICS, INC. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524943-B1 | Benzocarbonyl compounds | YAP1, TEAD2, TEAD3 | ABCG2 2776/4885NPSR1 4515/4885AKR1C3 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.