Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140977 | 0.86 | RAB9A (0.49) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL31336698 | 0.74 | RAB9A (0.39) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL4594309 | 0.74 | ALDH1A1 (0.40) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL9179037 | 0.74 | MAPK1 (0.56) | RAB9APOLBNPC1SMN1; SMN2MEN1 | |
| SCHEMBL27269496 | 0.73 | RAB9A (0.48) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL22437556 | 0.73 | SMN1; SMN2 (0.50) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL8308094 | 0.72 | POLB (0.59) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL16268552 | 0.71 | GAA (0.38) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL16797981 | 0.71 | GAA (0.39) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL10759709 | 0.71 | KMT2A (0.46) | POLBSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |
| EP-4110779-A1 | COMPOUNDS AND METHODS OF USE | Exelixis, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |