Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30062036 | 0.88 | HDAC1 (0.43) | HDAC1HDAC6FAAHTYRO3DHFR | |
| Trifluoroacetic Acid SCHEMBL30230512 | 0.88 | HDAC1 (0.43) | HDAC1HDAC6FAAHTYRO3DHFR | |
| Trifluoroacetic Acid SCHEMBL30474054 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL22556931 | 0.85 | FAAH (0.46) | HDAC1HDAC6FAAH | |
| SCHEMBL30060113 | 0.84 | HDAC1 (0.45) | HDAC1HDAC6FAAHTYRO3PIM1 | |
| SCHEMBL30060144 | 0.84 | HDAC1 (0.45) | HDAC1HDAC6FAAHTYRO3PIM1 | |
| SCHEMBL24073260 | 0.84 | HDAC1 (0.55) | HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL30474043 | 0.84 | HDAC1 (0.38) | HDAC1HDAC6FAAHTYRO3SLC5A1 | |
| Trifluoroacetic Acid SCHEMBL30474012 | 0.83 | HDAC1 (0.37) | HDAC1HDAC6FAAHSLC5A1PIM1 | |
| Trifluoroacetic Acid SCHEMBL30473991 | 0.83 | HDAC1 (0.37) | HDAC1HDAC6SLC5A1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132925-A1 | N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | Mission Therapeutics Limited (GB) | 2023-02-15 | — | — | EP | disclosed |
| CN-115461340-A | N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2022-12-09 | — | — | CN | disclosed |