Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 14/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685791 | 0.92 | EPHX1 (0.41) | EPHX1ACHEALDH1A1HPGDKDM4E | |
| SCHEMBL1954999 | 0.80 | EPHX1 (0.42) | EPHX1ACHEALDH1A1HPGDKDM4E | |
| SCHEMBL15312720 | 0.79 | EPHX1 (0.41) | EPHX1ACHEALDH1A1HPGDKDM4E | |
| SCHEMBL20447617 | 0.78 | MAPT (0.33) | ACHEMAPT | |
| SCHEMBL8303913 | 0.78 | EPHX1 (0.40) | EPHX1ACHEALDH1A1HPGDKDM4E | |
| SCHEMBL30292346 | 0.77 | EPHX1 (0.42) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL4722846 | 0.76 | ALDH1A1 (0.41) | EPHX1ACHEALDH1A1HPGDKDM4E | |
| SCHEMBL2722735 | 0.76 | EPHX1 (0.44) | EPHX1ACHEALDH1A1HPGDRAB9A | |
| SCHEMBL32678641 | 0.76 | EPHX1 (0.44) | EPHX1ACHEALDH1A1HPGDRAB9A | |
| SCHEMBL32678640 | 0.76 | EPHX1 (0.44) | EPHX1ACHEALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077283-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-10-26 | — | — | EP | disclosed |