Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21054627 | 1.00 | AKR1C3 (0.51) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL30062661 | 0.90 | AKR1C3 (0.45) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL21054808 | 0.90 | AKR1C3 (0.45) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL30062650 | 0.89 | ABCG2 (0.48) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL21054644 | 0.89 | ABCG2 (0.46) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL21055838 | 0.89 | ABCG2 (0.48) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL30063574 | 0.89 | AKR1C3 (0.43) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL21054916 | 0.89 | AKR1C3 (0.53) | AKR1C3AKR1C2TEAD4AKR1B1AKR1C4 | |
| SCHEMBL21090776 | 0.89 | AKR1C3 (0.43) | AKR1C3AKR1C2ABCG2TEAD1YAP1 | |
| SCHEMBL30061296 | 0.89 | AKR1C3 (0.53) | AKR1C3AKR1C2TEAD4AKR1B1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524943-B1 | Benzocarbonyl compounds | VIVACE THERAPEUTICS, INC. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524943-B1 | Benzocarbonyl compounds | YAP1, TEAD2, TEAD3 | AKR1C3 4086/4885AKR1C2 3536/4885ABCG2 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.