Dermaseptin S1

SCHEMBL30063560

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)O)[C@@H](C)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	PTH1R	Q03431	11/20	0.68

▸	GLP1R	P43220	5/20	0.67

▸	CCKBR	P32239	1/20	0.67

▸	ECE1	P42892	1/20	0.66

▸	MUS81	Q96NY9	1/20	0.66

▸	RXFP1	Q9HBX9	1/20	0.62

▸	SLC2A1	P11166	2/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Dermaseptin S1 SCHEMBL29388838	0.93	GLP1R (0.64)	GLP1RCCKBRRXFP1
SCHEMBL31578362	0.89	GLP1R (0.73)	PTH1RGLP1RCCKBRECE1MUS81
SCHEMBL30804687	0.89	GLP1R (0.66)	GLP1RCCKBRRXFP1
Teduglutide SCHEMBL20898050	0.89	GLP1R (0.82)	PTH1RGLP1RCCKBRECE1MUS81
Teduglutide SCHEMBL29373256	0.89	GLP1R (0.82)	PTH1RGLP1RCCKBRECE1MUS81
SCHEMBL29376455	0.89	PTH1R (0.81)	PTH1RGLP1RCCKBRECE1MUS81
SCHEMBL29370374	0.88	GLP1R (0.71)	PTH1RGLP1RCCKBRECE1MUS81
SCHEMBL29599165	0.88	GLP1R (0.65)	PTH1RGLP1RCCKBRRXFP1
Lycotoxin I SCHEMBL29412262	0.88	GLP1R (0.66)	PTH1RGLP1RCCKBRECE1MUS81
SCHEMBL31182833	0.87	PTH1R (0.70)	PTH1RGLP1RCCKBRECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240190928-A1	FUSION PEPTIDES OR PROTEINS, THEIR USE, AND SYSTEMS AND KITS BASED THEREUPON, FOR THE SEPARATION AND/OR DETECTION OF PLASTICS, PARTICULARLY OF MICROPLASTICS	DWI - LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE)	2024-06-13	—	—	US	claimed
EP-3129044-B1	PEPTIDOGLYCAN HYDROLASE FOR USE IN THE TREATMENT OF CHRONIC BACTERIAL INFECTIONS	LYSANDO AG (LI)	2022-09-07	—	—	EP	claimed
CN-119258284-A	Nano needle and preparation method and application thereof	国家纳米科学中心	2025-01-07	—	—	CN	disclosed
CN-118749585-A	Feed additive and preparation method and application thereof	唐山泰翔生物科技有限公司	2024-10-11	—	—	CN	disclosed
EP-3944763-B1	ASSEMBLY OF CARBON ATOMS IN FUNCTIONALISED SP2 HYBRIDISATION STATE, METHOD FOR PREPARING SAME AND USES THEREOF, IN PARTICULAR FOR MAKING A SURFACE ANTI-BACTERIAL	COMMISSARIAT ENERGIE ATOMIQUE (FR)	2024-07-17	—	—	EP	disclosed
US-20240190928-A1	FUSION PEPTIDES OR PROTEINS, THEIR USE, AND SYSTEMS AND KITS BASED THEREUPON, FOR THE SEPARATION AND/OR DETECTION OF PLASTICS, PARTICULARLY OF MICROPLASTICS	DWI - LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE)	2024-06-13	—	—	US	disclosed
US-20240011069-A1	BIOSENSOR COMPRISING A PLURALITY OF FUNCTIONALIZED SETS OF CARBON ATOMS IN THE SP2 HYBRIDISATION STATE, PREPARATION METHOD THEREOF AND USE THEREOF, IN PARTICULAR FOR THE DETECTION OF ECOTOXICOLOGICAL RISKS	COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR)	2024-01-11	—	—	US	disclosed
EP-4283298-A1	BIOSENSOR COMPRISING A PLURALITY OF FUNCTIONALISED SP2 HYBRIDIZATION CARBON ATOM SETS, METHOD FOR PREPARING SAME AND USE THEREOF, IN PARTICULAR FOR DETECTING ECO-TOXICOLOGICAL RISKS	Commissariat à l'énergie atomique et aux énergies alternatives (FR)	2023-11-29	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20240011069-A1	BIOSENSOR COMPRISING A PLURALITY OF FUNCTIONALIZED SETS OF CARBON ATOMS IN THE SP2 HYBRIDISATION STATE, PREPARATION METHOD THEREOF AND USE THEREOF, IN PARTICULAR FOR THE DETECTION OF ECOTOXICOLOGICAL RISKS	SP1, L3MBTL4, AS3MT	PTH1R 4446/4885GLP1R 4482/4885CCKBR 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.