Lycotoxin I

Lycotoxin I

SCHEMBL29412262

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 9/20 0.66
▸ ECE1 P42892 1/20 0.66
▸ MUS81 Q96NY9 1/20 0.66
▸ NPY1R P25929 1/20 0.63
▸ NPY2R P49146 1/20 0.63
▸ NPY4R P50391 1/20 0.63
▸ NPY5R Q15761 1/20 0.63
▸ NR3C1 P04150 4/20 0.62
▸ PTH1R Q03431 3/20 0.62
▸ CCKBR P32239 1/20 0.62
▸ SLC2A1 P11166 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683247 0.88 GLP1R (0.65) GLP1RECE1MUS81NPY1RNPY2R
Dermaseptin S1 SCHEMBL30063560 0.88 PTH1R (0.68) GLP1RECE1MUS81PTH1RCCKBR
SCHEMBL29408638 0.87 GHSR (0.62) —
SCHEMBL29370374 0.87 GLP1R (0.71) GLP1RECE1MUS81NPY1RNPY2R
SCHEMBL29358003 0.87 NR3C1 (0.66) GLP1RECE1MUS81NR3C1
SCHEMBL29534976 0.87 GLP1R (0.60) GLP1RCCKBR
SCHEMBL31578362 0.86 GLP1R (0.73) GLP1RECE1MUS81NR3C1PTH1R
SCHEMBL31060658 0.85 GLP1R (0.89) GLP1RECE1MUS81NR3C1PTH1R
Teduglutide SCHEMBL20898050 0.85 GLP1R (0.82) GLP1RECE1MUS81NR3C1PTH1R
SCHEMBL29748897 0.85 GLP1R (0.61) GLP1RECE1MUS81PTH1RCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747274-A2 PROTEIN-BASED DELIVERY SYSTEM Beth Israel Deaconess Medical Center, Inc. (US) 2026-05-27 — — EP claimed
WO-2025019713-A2 PROTEIN-BASED DELIVERY SYSTEM BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2025-01-23 — — WO claimed
CN-116179609-A Method for improving transfection efficiency of membrane-permeable polypeptide gene 中山大学附属第七医院(深圳) 2023-05-30 — — CN claimed
EP-3129044-B1 PEPTIDOGLYCAN HYDROLASE FOR USE IN THE TREATMENT OF CHRONIC BACTERIAL INFECTIONS LYSANDO AG (LI) 2022-09-07 — — EP claimed
EP-4747274-A2 PROTEIN-BASED DELIVERY SYSTEM Beth Israel Deaconess Medical Center, Inc. (US) 2026-05-27 — — EP disclosed
CN-122070299-A Cell penetrating agent and use thereof 普罗塞纳生物科学有限公司 2026-05-19 — — CN disclosed
EP-3574909-B1 POLYELECTROLYTE MULTILAYER COMPRISING SILVER FOR WOUND HEALING IMBED BIOSCIENCES INC (US) 2026-03-04 — — EP disclosed
US-20260022349-A1 ENHANCED VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLS MASSACHUSETTS GEN HOSPITAL (US) 2026-01-22 — — US disclosed
US-20260000805-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING IMBED BIOSCIENCES INC (US) 2026-01-01 — — US disclosed
US-20250375394-A1 METHODS AND COMPOSITIONS FOR MODIFYING MUCOUS MEMBRANES ABBOTT NICHOLAS L (US) 2025-12-11 — — US disclosed
US-12409247-B2 Methods and compositions for wound healing IMBED BIOSCIENCES INC. (US) 2025-09-09 — — US disclosed
US-12404525-B2 Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells THE GENERAL HOSPITAL CORPORATION (US) 2025-09-02 — — US disclosed
EP-4001295-A1 PEPTIDE THERAPEUTICS FOR AUTOIMMUNE DISEASES AND INFLAMMATORY DISEASES Genesen Co., Ltd. (KR) 2022-05-25 — — EP disclosed
EP-3995158-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING Imbed Biosciences, Inc. (US) 2022-05-11 — — EP disclosed
US-11325955-B2 Stabilized anti-microbial peptides for the treatment of antibiotic-resistant bacterial infections DANA-FARBER CANCER INSTITUTE, INC. (US) 2022-05-10 — — US disclosed
EP-3982989-A1 ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLS The General Hospital Corporation (US) 2022-04-20 — — EP disclosed
EP-3978605-A1 ANTIMICROBIAL AGENTS AGAINST SALMONELLA BACTERIA Lysando AG (LI) 2022-04-06 — — EP disclosed
EP-3541406-B1 NEW ANTIMICROBIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS LYSANDO AG (LI) 2022-03-16 — — EP disclosed
US-20220064623-A1 ENDOLYSIN VARIANT SASINAPAS CO., LTD. (TH) 2022-03-03 — — US disclosed
WO-2022020800-A2 ENHANCED VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLS THE GENERAL HOSPITAL CORPORATION (US) 2022-01-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022349-A1 ENHANCED VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLS PLTP, TMIGD3, APOL1 GLP1R 2734/4885ECE1 2908/4885MUS81 1537/4885
US-20260000805-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING PCNA, ARG1, PLOD3 GLP1R 4075/4885ECE1 3033/4885MUS81 2607/4885
US-11325955-B2 Stabilized anti-microbial peptides for the treatment of antibiotic-resistant bacterial infections MME, CLPP, VIP GLP1R 347/4885ECE1 976/4885MUS81 2383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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