SCHEMBL30064

SCHEMBL30064

Cc1ccc(C)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.42
HPGD P15428 1/20 0.41
CYP1A2 P05177 2/20 0.39
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.36
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175646 0.87 ACHE (0.41) ACHEHPGDCYP1A2HTTHDAC1
SCHEMBL12023277 0.87 POLB (0.38) ACHEHPGDCYP1A2TSHRHTT
SCHEMBL67359 0.87 ACHE (0.41) ACHEHPGDCYP1A2HTTHDAC1
SCHEMBL18069659 0.87 POLB (0.38) ACHEHPGDCYP1A2TSHRHTT
SCHEMBL31633781 0.82 ACHE (0.36) ACHEHPGDCYP1A2TSHRHDAC1
SCHEMBL15496486 0.82 CYP1A2 (0.40) ACHEHPGDCYP1A2TSHRALDH1A1
SCHEMBL144695 0.82 ACHE (0.36) ACHEHPGDCYP1A2TSHRHDAC1
SCHEMBL19160972 0.82 HPGD (0.34) ACHEHPGDHTT
SCHEMBL10595962 0.82 HTR2A (0.42) ACHEHPGDHTR2AHTR2CHTR2B
SCHEMBL13765703 0.82 HPGD (0.34) ACHEHPGDHTTHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3264 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417531-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-12-19 US claimed
EP-4419603-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-08-28 EP claimed
WO-2023067111-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2023-04-27 WO claimed
US-20240417531-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-12-19 US disclosed
EP-4419603-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-08-28 EP disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed
US-20060211895-A1 Method for synthesizing TFPX YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) 2006-09-21 US disclosed
WO-2006056930-A2 NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2006-06-01 WO disclosed
CN-1127461-C Process for synthesizing alpha position perfluoro-p-xylene polymer SHANGHAI INST ORGANIC CHEM (CN) 2003-11-12 CN disclosed
CN-1295996-A Process for synthesizing alpha position perfluoro-p-xylene polymer SHANGHAI INST ORGANIC CHEM (CN) 2001-05-23 CN disclosed
EP-0285324-B1 PREPARATION OF SUBSTITUTED FLUOROBENZENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-27 EP disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed
EP-0285324-A1 Preparation of substituted fluorobenzenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-05 EP disclosed
US-4754084-A PYROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-28 US disclosed