Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | CCKAR | P32238 | 4/20 | 0.48 |
| ▸ | CCKBR | P32239 | 4/20 | 0.48 |
| ▸ | IL23R | Q5VWK5 | 7/20 | 0.48 |
| ▸ | TFPI | P10646 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750403 | 0.86 | OPRD1 (0.57) | OPRD1CCKARCCKBR | |
| Ascaphin-8 SCHEMBL29875628 | 0.86 | TFPI (0.58) | OPRD1TFPI | |
| SCHEMBL27379012 | 0.85 | TFPI (0.49) | F2TFPI | |
| SCHEMBL38658103 | 0.85 | BACE1 (0.50) | TFPI | |
| SCHEMBL31385126 | 0.84 | TFPI (0.63) | OPRD1TFPI | |
| SCHEMBL29701318 | 0.83 | OPRD1 (0.57) | OPRD1CCKARCCKBR | |
| SCHEMBL30880906 | 0.83 | TFPI (0.58) | IL23RTFPI | |
| SCHEMBL29464031 | 0.82 | CTSB (0.48) | F2OPRD1 | |
| SCHEMBL30138974 | 0.82 | CALCRL (0.55) | F2 | |
| SCHEMBL29574640 | 0.82 | SLC15A2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230001010-A1 | COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-01-05 | — | — | US | disclosed |