SCHEMBL30065149

SCHEMBL30065149

C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.62
▸ KLK7 P49862 2/20 0.60
▸ KLK5 Q9Y337 2/20 0.60
▸ ABCB1 P08183 1/20 0.54
▸ ITGB3 P05106 1/20 0.53
▸ ITGA2B P08514 1/20 0.53
▸ FOLH1 Q04609 1/20 0.53
▸ PAX8 Q06710 1/20 0.53
▸ TDP1 Q9NUW8 1/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30340359 0.92 MAPT (0.60) MAPTKLK7KLK5ITGB3ITGA2B
SCHEMBL17309872 0.92 MAPT (0.68) MAPTKLK7KLK5ABCB1ITGB3
SCHEMBL1303931 0.92 MAPT (0.68) MAPTKLK7KLK5ABCB1ITGB3
SCHEMBL13599694 0.91 MAPT (0.56) MAPTKLK7KLK5FOLH1PAX8
SCHEMBL30668140 0.89 KLK7 (0.57) MAPTKLK7KLK5ITGB3ITGA2B
SCHEMBL29460426 0.89 KLK7 (0.61) MAPTKLK7KLK5ABCB1ITGB3
SCHEMBL10035709 0.89 SYK (0.54) MAPTKLK7KLK5ITGB3ITGA2B
SCHEMBL8955505 0.89 KLK7 (0.64) MAPTKLK7KLK5ABCB1ITGB3
SCHEMBL30064541 0.88 MAPT (0.62) MAPTKLK7KLK5ABCB1ITGB3
SCHEMBL26016962 0.88 MAPT (0.54) MAPTKLK7KLK5FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4538279-A2 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2025-04-16 — — EP disclosed
US-20230121469-A1 CATALYST FOR MANUFACTURING AMIDE COMPOUND, AND METHOD FOR MANUFACTURING AMIDE COMPOUND CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-04-20 — — US disclosed
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-01-05 — — US disclosed
EP-4053132-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2022-09-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME NAAA, NOTUM, ASNS MAPT 4225/4885KLK7 3281/4885KLK5 2966/4885
US-20230121469-A1 CATALYST FOR MANUFACTURING AMIDE COMPOUND, AND METHOD FOR MANUFACTURING AMIDE COMPOUND NAAA, ASNS, BCAT2 MAPT 3585/4885KLK7 1452/4885KLK5 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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