Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22555255 | 1.00 | LPL (0.42) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL23043319 | 0.88 | LPL (0.42) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL30876507 | 0.88 | LPL (0.42) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL29634815 | 0.88 | LPL (0.42) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL30065204 | 0.84 | LPL (0.43) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL22555118 | 0.84 | LPL (0.43) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL30369989 | 0.83 | JAK2 (0.39) | LPLLIPGJAK2BTK | |
| SCHEMBL25177449 | 0.83 | JAK2 (0.39) | LPLLIPGJAK2BTK | |
| SCHEMBL23043114 | 0.83 | CYP1A2 (0.49) | LPLLIPGJAK2BTKCYP1A2 | |
| SCHEMBL23569435 | 0.81 | ESR1 (0.39) | LPLLIPGJAK2BTKCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511127-A1 | KRAS G12D MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205719-A1 | KRAS G12D MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-4087573-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |