SCHEMBL30065446

SCHEMBL30065446

Brc1ccc2c(c1)Nc1ccc(Br)cc1S2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 6/20 0.58
NOX1 Q9Y5S8 13/20 0.48
GAA P10253 4/20 0.48
MAPT P10636 4/20 0.48
MAPK1 P28482 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 2/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
ALOX12 P18054 1/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205578 1.00 SNCA (0.58) SNCANOX1GAAMAPTMAPK1
SCHEMBL28407357 0.92 SNCA (0.47) SNCANOX1GAAMAPTMAPK1
SCHEMBL2582828 0.92 SNCA (0.66) SNCANOX1GAAMAPTMAPK1
SCHEMBL29637682 0.92 SNCA (0.66) SNCANOX1GAAMAPTMAPK1
Bromide SCHEMBL30448580 0.90 SNCA (0.64) SNCANOX1GAAMAPTMAPK1
Bromide SCHEMBL20495634 0.90 SNCA (0.64) SNCANOX1GAAMAPTMAPK1
SCHEMBL28635096 0.88 NOX1 (0.65) SNCANOX1GAAMAPTMAPK1
SCHEMBL4706809 0.86 SNCA (0.45) SNCANOX1GAAMAPTMAPK1
SCHEMBL30769565 0.86 NOX1 (0.65) SNCANOX1GAAMAPTMAPK1
SCHEMBL239782 0.86 NOX1 (0.65) SNCANOX1GAAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490854-B Polyimide with low dielectric, high heat resistance and low water absorption and high performance, and preparation method and application thereof 江西有泽新材料科技有限公司 2024-01-30 CN claimed
CN-115490854-A Low-dielectric, high-heat-resistant and low-water-absorption high-performance polyimide, and preparation method and application thereof 江西有泽新材料科技有限公司 2022-12-20 CN claimed
CN-113429399-B Pyrene derivative, light-emitting device material and light-emitting device 浙江华显光电科技有限公司 2024-03-26 CN disclosed
CN-115490854-B Polyimide with low dielectric, high heat resistance and low water absorption and high performance, and preparation method and application thereof 江西有泽新材料科技有限公司 2024-01-30 CN disclosed
CN-115490854-A Low-dielectric, high-heat-resistant and low-water-absorption high-performance polyimide, and preparation method and application thereof 江西有泽新材料科技有限公司 2022-12-20 CN disclosed