SCHEMBL2582828

SCHEMBL2582828

Brc1ccc2c(c1)Sc1cc(Br)ccc1N2

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 7/20 0.66
NOX1 Q9Y5S8 9/20 0.47
GAA P10253 3/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
MAOA P21397 1/20 0.46
CNR1 P21554 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637682 1.00 SNCA (0.66) SNCANOX1GAAMAPTMEN1
Bromide SCHEMBL20495634 0.98 SNCA (0.64) SNCANOX1GAAMAPTMEN1
Bromide SCHEMBL30448580 0.98 SNCA (0.64) SNCANOX1GAAMAPTMEN1
SCHEMBL30065446 0.92 SNCA (0.58) SNCANOX1GAAMAPTMEN1
SCHEMBL205578 0.92 SNCA (0.58) SNCANOX1GAAMAPTMEN1
SCHEMBL30769565 0.90 NOX1 (0.65) SNCANOX1GAAMAPTMEN1
SCHEMBL239782 0.90 NOX1 (0.65) SNCANOX1GAAMAPTMEN1
SCHEMBL4708193 0.90 SNCA (0.57) SNCANOX1GAAMAPTMEN1
SCHEMBL9391898 0.88 SNCA (0.55) SNCANOX1GAAMAPTMEN1
SCHEMBL19744465 0.85 NOX1 (0.57) SNCANOX1GAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521456-B Polyimide for glue-free flexible copper-clad plate and preparation method thereof 江西有泽新材料科技有限公司 2023-07-21 CN claimed
CN-116239546-A Force response pure organic multiple luminescent material based on 5, 5-phenothiazine dioxide and preparation method thereof 天津大学 2023-06-09 CN claimed
CN-115521456-A Polyimide for glue-free flexible copper clad laminate and preparation method thereof 江西有泽新材料科技有限公司 2022-12-27 CN claimed
CN-112441992-A Nitrogen-containing heterocyclic compound and soluble porous polymer 华南理工大学 2021-03-05 CN claimed
US-20180057471-A1 Two-Electron Donating Phenothiazines and Use Thereof UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2018-03-01 US claimed
US-9590190-B2 Terminally activated delayed fluorescence material, a method of synthesizing the same and an OLED device using the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2017-03-07 US claimed
CN-103694992-B Hot activation delayed fluorescence material, its synthetic method and use the OLED of this hot activation delayed fluorescence material SHENZHEN HUAXING OPTOELECTRONIC TECHNOLOGY CO., LTD. (CN) 2016-03-16 CN claimed
CN-103204826-B One prepares the method for 3,7-dibromo thiodiphenylamine SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-02-10 CN claimed
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-09-24 US claimed
CN-103694992-A Thermal activation delay fluorescent material and synthesis method thereof as well as OLED device using thermal activation delay fluorescent material SHENZHEN HUAXING OPTOELECT TEC 2014-04-02 CN claimed
CN-103204826-A Method for preparing 3, 7-dibromophenothiazin UNIV SHAANXI SCIENCE & TECH 2013-07-17 CN claimed
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
US-20250393469-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-12-25 US disclosed
EP-4651874-A2 PHENOTHIAZINYL COMPOUNDS AND USES Prosetta Biosciences, Inc. (US) 2025-11-26 EP disclosed
US-12433150-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-30 US disclosed
WO-2011137447-A1 ANTIVIRAL COMPOUNDS PROSTETTA ANTIVIRAL INC. (US) 2011-11-03 WO disclosed
US-20110178071-A1 Antiviral Treatments PROSETTA CORPORATION 2011-07-21 US disclosed
WO-2008124550-A1 PHENOTHIAZIN DERIVATIVES FOR ANTIVIRAL TREATMENTS PROSETTA CORPORATION (US) 2008-10-16 WO disclosed
US-5756356-A COLORIMETRIC TOYO INK MANUFACTURING CO., LTD. (JP) 1998-05-26 US disclosed
EP-0735368-A1 Method of indicating time or temperature-time accumulated value as color change, and materials therefor TOYO INK MANUFACTURING CO., LTD. (JP) 1996-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12433150-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device ODC1, LEF1, L1CAM SNCA 2281/4885NOX1 970/4885GAA 1983/4885
US-20250393469-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SOD1, LIFR, LEF1 SNCA 295/4885NOX1 11/4885GAA 2650/4885
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 SNCA 643/4885NOX1 211/4885GAA 1109/4885
US-20180057471-A1 Two-Electron Donating Phenothiazines and Use Thereof SLC6A12, SLCO1B3, SLCO1A2 SNCA 1505/4885NOX1 3353/4885GAA 2947/4885
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same OCIAD1, OCIAD2, OGFOD1 SNCA 1416/4885NOX1 901/4885GAA 2399/4885
US-20110178071-A1 Antiviral Treatments HAVCR2, MAVS, EIF2AK2 SNCA 862/4885NOX1 2537/4885GAA 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.