Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 3/20 | 0.62 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928647 | 1.00 | SORT1 (0.62) | SORT1SCN10ASCN8AHDAC4HDAC6 | |
| SCHEMBL28651365 | 0.85 | SORT1 (0.48) | SORT1SCN10AHDAC4HDAC6 | |
| SCHEMBL30065560 | 0.85 | SORT1 (0.48) | SORT1SCN10AHDAC4HDAC6 | |
| SCHEMBL22852836 | 0.83 | SORT1 (0.63) | SORT1SCN10ASCN8AHDAC4HDAC6 | |
| SCHEMBL30294517 | 0.83 | SORT1 (0.63) | SORT1SCN10ASCN8AHDAC4HDAC6 | |
| SCHEMBL22502631 | 0.83 | SCN10A (0.66) | SORT1SCN10ASCN8A | |
| SCHEMBL23099928 | 0.80 | LRRK2 (0.56) | LRRK2 | |
| SCHEMBL15901600 | 0.80 | SORT1 (0.78) | SORT1SCN10ASCN8AHDAC4HDAC6 | |
| SCHEMBL30065546 | 0.79 | SCN8A (0.68) | SCN10ASCN8A | |
| SCHEMBL28661344 | 0.79 | SCN8A (0.68) | SCN10ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996774-B | 2-oxo-1,2-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |