Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22555283 | 1.00 | RIPK1 (0.33) | RIPK1MCL1GRM5 | |
| SCHEMBL30070935 | 0.90 | USP30 (0.37) | GRM5 | |
| SCHEMBL26694476 | 0.86 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL23043370 | 0.86 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL4120850 | 0.86 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL29889630 | 0.85 | KMT2A (0.36) | RIPK1 | |
| SCHEMBL22554958 | 0.85 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL30065094 | 0.85 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL4105456 | 0.78 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL2645429 | 0.77 | UCHL1 (0.39) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087573-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |