Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | IL1RN | P18510 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728853 | 1.00 | OPRM1 (0.48) | OPRM1OPRD1ACEOPRK1FOLH1 | |
| SCHEMBL30728852 | 0.95 | OPRM1 (0.52) | OPRM1OPRD1ACEOPRK1IL1RN | |
| SCHEMBL29986177 | 0.95 | OPRM1 (0.52) | OPRM1OPRD1ACEOPRK1IL1RN | |
| SCHEMBL29993760 | 0.88 | NPY4R (0.53) | OPRM1OPRD1ACEOPRK1FOLH1 | |
| SCHEMBL30034864 | 0.88 | NPY1R (0.53) | OPRM1OPRD1ACEFOLH1NPY1R | |
| SCHEMBL29705780 | 0.88 | OPRD1 (0.54) | OPRM1OPRD1ACEOPRK1FOLH1 | |
| SCHEMBL29815237 | 0.87 | NPY4R (0.51) | OPRM1OPRD1OPRK1FOLH1NPY1R | |
| SCHEMBL5598789 | 0.86 | MME (0.46) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL5598794 | 0.86 | MME (0.46) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL30692732 | 0.86 | MME (0.46) | ACEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322258-A | Monoclonal antibody QKMA-1G41 and application thereof | 武汉真福医药股份有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-115322258-A | Monoclonal antibody QKMA-1G41 and application thereof | 武汉真福医药股份有限公司 | 2022-11-11 | — | — | CN | disclosed |