Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ODC1 | P11926 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191747 | 0.88 | ODC1 (0.41) | KDM4EMAPTGAAMAPK1HTT | |
| SCHEMBL30065894 | 0.88 | ODC1 (0.41) | KDM4EMAPTGAAMAPK1HTT | |
| SCHEMBL30065930 | 0.72 | KDM4E (0.40) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL27212233 | 0.72 | ALDH1A1 (0.44) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL14922296 | 0.71 | HTR3A (0.47) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL14922288 | 0.70 | KDM4E (0.49) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL23123741 | 0.69 | KDM4E (0.44) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL29789858 | 0.69 | KDM4E (0.44) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL31254058 | 0.68 | PTPN1 (0.52) | KDM4EMAPTODC1NPC1RAB9A | |
| SCHEMBL30065835 | 0.68 | HTR2C (0.54) | KDM4EMAPTODC1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023277656-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | (주)스파크바이오파마 | 2023-01-05 | — | — | WO | disclosed |