SCHEMBL30067289

SCHEMBL30067289

O=C1CCCc2ccc(OCc3ccccc3)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 20/20 1.00
MAOA P21397 19/20 1.00
NPC1 O15118 1/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
NFKB1 P19838 1/20 0.56
GRM5 P41594 1/20 0.56
RAB9A P51151 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3501723 1.00 MAOB (1.00) MAOBMAOANPC1ALDH1A1HPGD
SCHEMBL7215662 0.97 MAOB (0.94) MAOBMAOANPC1ALDH1A1HPGD
SCHEMBL2524800 0.91 MAOB (0.84) MAOBMAOANPC1ALDH1A1HPGD
SCHEMBL30353268 0.91 MAOB (0.84) MAOBMAOANPC1ALDH1A1HPGD
SCHEMBL7218099 0.91 MAOB (0.82) MAOBMAOANPC1ALDH1A1HPGD
SCHEMBL226640 0.89 MAOB (1.00) MAOBMAOANPC1ALDH1A1HPGD
SCHEMBL6309072 0.86 MAOB (1.00) MAOBMAOA
SCHEMBL7184607 0.86 MAOA (0.76) MAOBMAOANPC1RAB9A
SCHEMBL15414670 0.86 MAOB (0.81) MAOBMAOA
SCHEMBL3451690 0.86 MAOB (0.94) MAOBMAOANPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074043-A Combination therapy with KRAS modulators 光达治疗公司 2026-05-22 CN disclosed
WO-2025034883-A1 COMBINATION THERAPIES WITH KRAS MODULATORS QUANTA THERAPEUTICS, INC. (US) 2025-02-13 WO disclosed
WO-2025034919-A1 COMBINATION THERAPIES WITH KRAS MODULATORS QUANTA THERAPEUTICS, INC. (US) 2025-02-13 WO disclosed
EP-4475956-A1 KRAS MODULATORS AND USES THEREOF Quanta Therapeutics, Inc. (US) 2024-12-18 EP disclosed
CN-119110804-A KRAS modulators and uses thereof 光达治疗公司 2024-12-10 CN disclosed
WO-2023154766-A1 KRAS MODULATORS AND USES THEREOF QUANTA THERAPEUTICS, INC. (US) 2023-08-17 WO disclosed
WO-2022240971-A2 KRAS G12D INHIBITORS AND USES THEREOF 1200 PHARMA LLC (US) 2022-11-17 WO disclosed