Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 20/20 | 0.94 |
| ▸ | MAOA | P21397 | 19/20 | 0.94 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067289 | 0.97 | MAOB (1.00) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL3501723 | 0.97 | MAOB (1.00) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL7218099 | 0.93 | MAOB (0.82) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL2524800 | 0.91 | MAOB (0.84) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL30353268 | 0.91 | MAOB (0.84) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL3451690 | 0.89 | MAOB (0.94) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL7222729 | 0.87 | MAOB (0.97) | MAOBMAOA | |
| SCHEMBL6309072 | 0.86 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL226640 | 0.86 | MAOB (1.00) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL2314862 | 0.85 | MAOB (0.74) | MAOBMAOANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106415244-B | Reactive marker compounds and uses thereof | 中央研究院 | 2020-04-24 | — | — | CN | disclosed |
| US-10119972-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2018-11-06 | — | — | US | disclosed |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-01-11 | — | — | US | disclosed |
| US-9759726-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-09-12 | — | — | US | disclosed |
| US-9759726-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-09-12 | — | — | US | disclosed |
| EP-3129767-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | Academia Sinica (TW) | 2017-02-15 | — | — | EP | disclosed |
| US-9547009-B2 | Benzocyclooctyne compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-01-17 | — | — | US | disclosed |
| WO-2015148915-A9 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2016-12-22 | — | — | WO | disclosed |
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-29 | — | — | US | disclosed |
| WO-2015148915-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-01 | — | — | WO | disclosed |
| US-20150241439-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-08-27 | — | — | US | disclosed |
| EP-2888238-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | Academia Sinica (TW) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014031762-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2014-02-27 | — | — | WO | disclosed |
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | MAOB 23/4885MAOA 135/4885NPC1 617/4885 |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | MAOB 20/4885MAOA 135/4885NPC1 688/4885 |
| US-20150241439-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | AADAC, TBCA, SPG11 | MAOB 23/4885MAOA 104/4885NPC1 3214/4885 |
| US-10119972-B2 | Reactive labelling compounds and uses thereof | MPI, AADAC, PAICS | MAOB 20/4885MAOA 135/4885NPC1 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.