Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 14/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | PNLIP | P16233 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCL9 | O00512 | 3/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rosmadial SCHEMBL13294494 | 0.77 | FDPS (0.60) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL30100263 | 0.68 | FDPS (0.39) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Standishinal SCHEMBL30172865 | 0.67 | FDPS (0.38) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Pisiferal SCHEMBL29361829 | 0.60 | KARS1 (0.66) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL18290374 | 0.60 | FDPS (0.49) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL18290367 | 0.60 | FDPS (0.50) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL17388698 | 0.59 | KARS1 (0.48) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL16006712 | 0.59 | KARS1 (0.48) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL18290299 | 0.59 | KARS1 (0.48) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL18290217 | 0.58 | KARS1 (0.47) | FDPSGGPS1PTGESPNLIPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12246052-B2 | Antimicrobial hevamine A-related compositions and methods | MOREHOUSE SCHOOL OF MEDICINE | 2025-03-11 | — | — | US | disclosed |
| US-20240325481-A1 | ANTIMICROBIAL HEVAMINE A-RELATED COMPOSITIONS AND METHODS | MOREHOUSE SCHOOL OF MEDICINE | 2024-10-03 | — | — | US | disclosed |
| EP-4351622-A1 | ANTIMICROBIAL HEVAMINE A-RELATED COMPOSITIONS AND METHODS | Morehouse School of Medicine (US) | 2024-04-17 | — | — | EP | disclosed |
| US-11925670-B2 | Antimicrobial hevamine A-related compositions and methods | MOREHOUSE SCHOOL OF MEDICINE (US) | 2024-03-12 | — | — | US | disclosed |
| US-20220401527-A1 | ANTIMICROBIAL HEVAMINE A-RELATED COMPOSITIONS AND METHODS | MOREHOUSE SCHOOL OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
| WO-2022261067-A1 | ANTIMICROBIAL HEVAMINE A-RELATED COMPOSITIONS AND METHODS | MOREHOUSE SCHOOL OF MEDICINE (US) | 2022-12-15 | — | — | WO | disclosed |