Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23389139 | 1.00 | EIF4A3 (0.50) | EIF4A3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL18239638 | 0.83 | SRD5A1 (0.58) | EIF4A3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL1144949 | 0.82 | SRD5A2 (0.56) | EIF4A3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL25991354 | 0.79 | HRH4 (0.51) | KMT2A | |
| SCHEMBL1822934 | 0.79 | EIF4A3 (0.68) | EIF4A3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL31287808 | 0.76 | KDM4E (0.56) | EIF4A3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL1144612 | 0.76 | EIF4A3 (0.60) | EIF4A3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL23419026 | 0.75 | AXL (0.38) | KDM4EIDO1TDO2KMT2AMAPT | |
| SCHEMBL23418847 | 0.75 | EHMT2 (0.50) | KDM4EIDO1TDO2KMT2AGAA | |
| SCHEMBL23419229 | 0.75 | EPHX2 (0.33) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335039-A | Caspase 6 inhibitors and uses thereof | 加利福尼亚大学董事会 | 2022-11-11 | — | — | CN | disclosed |