Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287689 | 0.83 | KDM4E (0.58) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL30071322 | 0.82 | KMT2A (0.61) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL20494611 | 0.82 | KMT2A (0.61) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL31287858 | 0.82 | KMT2A (0.78) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL1144949 | 0.79 | SRD5A2 (0.56) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL914933 | 0.77 | SRD5A2 (0.56) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL23389139 | 0.76 | EIF4A3 (0.50) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL30068484 | 0.76 | EIF4A3 (0.50) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL1822934 | 0.76 | EIF4A3 (0.68) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 | |
| SCHEMBL31287891 | 0.74 | LGALS8 (0.59) | KDM4EHPGDHSD17B10ALDH1A1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852135-A | N-acyl sulfonamide compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-10-29 | — | — | CN | disclosed |