Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GSK3B | P49841 | 4/20 | 0.59 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433264 | 1.00 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6950333 | 0.92 | HTR4 (0.56) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6957369 | 0.89 | GSK3B (0.70) | SMN1; SMN2KDM4EGSK3BDYRK1A | |
| SCHEMBL16321074 | 0.85 | GSK3B (0.75) | GSK3BFLT3 | |
| SCHEMBL6952214 | 0.83 | GSK3B (0.62) | GSK3B | |
| SCHEMBL4253118 | 0.83 | CNR1 (0.66) | RAB9ANPC1KDM4EMAPK10HSD17B10 | |
| SCHEMBL3268402 | 0.82 | GSK3B (0.80) | GSK3BCCNA2CDK2FLT3CCNA1 | |
| SCHEMBL4253545 | 0.81 | CNR1 (0.67) | KDM4EGSK3BMAPK10HSD17B10CCNA2 | |
| SCHEMBL19101740 | 0.80 | GSK3B (0.68) | GSK3BDYRK1ACDK2 | |
| SCHEMBL1406015 | 0.80 | GSK3B (0.68) | GSK3BDYRK1ACDK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112673000-B | 1H-indazole carboxamides as receptor interacting protein kinase 1 inhibitors (RIPK 1) | 百时美施贵宝公司 | 2024-10-18 | — | — | CN | claimed |