Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26440123 | 1.00 | S1PR1 (0.39) | S1PR1S1PR5PDGFRAENPP2ATXN2 | |
| SCHEMBL26440334 | 0.83 | SIGMAR1 (0.45) | S1PR1S1PR5PDGFRAALDH1A1SMN1; SMN2 | |
| SCHEMBL14336170 | 0.79 | CYP3A4 (0.36) | SMN1; SMN2HTTHTR2CCYP3A4 | |
| SCHEMBL30069842 | 0.74 | DRD4 (0.40) | MEN1KMT2ASIGMAR1HTTHTR2C | |
| SCHEMBL26440261 | 0.74 | DRD4 (0.40) | MEN1KMT2ASIGMAR1HTTHTR2C | |
| SCHEMBL4795172 | 0.71 | SCD (0.43) | NR4A2ALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL30069894 | 0.71 | SCD (0.43) | NR4A2ALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL30069844 | 0.71 | HTT (0.42) | NR4A2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26440108 | 0.71 | HTT (0.42) | NR4A2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26440184 | 0.71 | POLB (0.43) | NR4A2SMN1; SMN2KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| EP-4087560-A2 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | Axial Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | SNCA, PARK7, PRNP | S1PR1 3668/4885S1PR5 4025/4885PDGFRA 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.