Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 11/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | DCAF1 | Q9Y4B6 | 2/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300451 | 0.91 | CNR2 (0.42) | CNR2MAPK1NPC1PAK4CNR1 | |
| SCHEMBL176745 | 0.87 | CNR2 (0.59) | CNR2MAPK1NPC1ALDH1A1LMNA | |
| SCHEMBL13011106 | 0.87 | CNR2 (0.59) | CNR2MAPK1NPC1ALDH1A1LMNA | |
| SCHEMBL13011108 | 0.87 | CNR2 (0.59) | CNR2MAPK1NPC1ALDH1A1LMNA | |
| SCHEMBL14089791 | 0.81 | CNR2 (0.52) | CNR2MAPK1NPC1ALDH1A1LMNA | |
| SCHEMBL300525 | 0.79 | CNR1 (0.46) | CNR2MAPK1ALDH1A1LMNACNR1 | |
| SCHEMBL300660 | 0.79 | CNR1 (0.46) | CNR2MAPK1ALDH1A1LMNACNR1 | |
| SCHEMBL176588 | 0.78 | CNR2 (0.53) | CNR2MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13011102 | 0.76 | CNR1 (0.51) | CNR2MAPK1NPC1ALDH1A1LMNA | |
| SCHEMBL13011107 | 0.76 | CNR1 (0.51) | CNR2MAPK1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |