Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.46 |
| ▸ | CNR2 | P34972 | 8/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300525 | 1.00 | CNR1 (0.46) | CNR1CNR2ATML3MBTL1ALDH1A1 | |
| SCHEMBL300451 | 0.88 | CNR2 (0.42) | CNR1CNR2MAPK1 | |
| SCHEMBL176790 | 0.86 | CNR1 (0.56) | CNR1CNR2ALDH1A1THRBLMNA | |
| SCHEMBL176483 | 0.86 | CNR1 (0.56) | CNR1CNR2ALDH1A1THRBLMNA | |
| SCHEMBL300543 | 0.83 | MAPK1 (0.35) | CNR1CNR2MAPK1 | |
| SCHEMBL300665 | 0.83 | MAPK1 (0.35) | CNR1CNR2MAPK1 | |
| SCHEMBL300699 | 0.79 | CNR2 (0.48) | CNR1CNR2ALDH1A1LMNAMAPK1 | |
| SCHEMBL300552 | 0.79 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL300698 | 0.78 | LIPE (0.48) | CNR1CNR2 | |
| SCHEMBL300514 | 0.77 | CNR1 (0.63) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |