Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300699 | 0.91 | CNR2 (0.48) | CNR2CNR1NPC1MAPK1PAK4 | |
| SCHEMBL300525 | 0.88 | CNR1 (0.46) | CNR2CNR1MAPK1 | |
| SCHEMBL300660 | 0.88 | CNR1 (0.46) | CNR2CNR1MAPK1 | |
| SCHEMBL176588 | 0.87 | CNR2 (0.53) | CNR2CNR1NPC1HTTMAPK1 | |
| SCHEMBL300543 | 0.78 | MAPK1 (0.35) | CNR2CNR1NPC1HTTMAPK1 | |
| SCHEMBL300665 | 0.78 | MAPK1 (0.35) | CNR2CNR1NPC1HTTMAPK1 | |
| SCHEMBL14089571 | 0.78 | CNR2 (0.47) | CNR2CNR1NPC1MAPK1PAK4 | |
| SCHEMBL176745 | 0.78 | CNR2 (0.59) | CNR2CNR1NPC1MAPK1PAK4 | |
| SCHEMBL13011106 | 0.77 | CNR2 (0.59) | CNR2CNR1NPC1MAPK1PAK4 | |
| SCHEMBL13011108 | 0.77 | CNR2 (0.59) | CNR2CNR1NPC1MAPK1PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |