⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8820148 | 0.97 | — | — | |
| SCHEMBL29080146 | 0.92 | — | — | |
| Dimethylamine SCHEMBL9453484 | 0.90 | CHRM2 (0.31) | — | |
| SCHEMBL17038687 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL300703 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL15017471 | 0.79 | — | — | |
| SCHEMBL7619160 | 0.79 | CXCR4 (0.47) | — | |
| SCHEMBL2055336 | 0.77 | — | — | |
| SCHEMBL24481218 | 0.74 | — | — | |
| SCHEMBL28833561 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364364-A | Liposome complex and cosmetic composition for skin improvement comprising same | 韩国科玛株式会社 | 2022-04-15 | — | — | CN | claimed |
| CN-118373768-A | Preparation method of 3-methylene (benzyl) piperidine | 泰州学院 | 2024-07-23 | — | — | CN | disclosed |
| CN-114057740-B | Spiropyrimidinone derivatives, method for the production thereof, pharmaceutical compositions and use thereof | 上海赛默罗生物科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2024015863-A1 | CBL-B INHIBITOR, COMPOSITIONS COMPRISING A CBL-B INHIBITOR IN A METHOD OF TREATING A DISEASE ASSOCIATED WITH CELL PROLIFERATION | HOTSPOT THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| US-20230250103-A1 | PROCESS FOR PREPARING BTK INHIBITORS | GENENTECH, INC. (US) | 2023-08-10 | — | — | US | disclosed |
| US-11685745-B2 | Substituted benzoxazole and benzofuran compounds as PDE7 inhibitors | DART NEUROSCIENCE, LLC (US) | 2023-06-27 | — | — | US | disclosed |
| US-11661424-B2 | Process for preparing BTK inhibitors | GENENTECH, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| CN-114057740-A | Spirocyclic pyrimidone derivatives, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | disclosed |
| CN-106102706-B | O/W emulsion composition | 株式会社高丝 | 2019-08-27 | — | — | CN | disclosed |
| EP-1542680-B1 | 1, 4, 5-SUBSTITUTED 1, 2-DIHYDRO-PYRAZOL-3-ONE AND 3-ALKOXY-1H-PYRAZOLE DERIVATIVES AS TNF-ALPHA AND INTERLEUKIN LOWERING AGENTS FOR THE TREATMENT OF INFLAMMATIONS | AMGEN INC (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1664053-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2007-01-24 | — | — | EP | disclosed |
| CN-1636550-A | Water-in-oil emulsion composition | SHISEIDO CO LTD (JP) | 2005-07-13 | — | — | CN | disclosed |
| CN-1162144-C | Ultraviolet absorbing composition | ������������ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| CN-1451732-A | Cleaner composition | KAO CORP (JP) | 2003-10-29 | — | — | CN | disclosed |
| CN-1449274-A | Hair growers | SHISEIDO CO LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| CN-1172641-A | Ultraviolet absorbing composition | SHISEIDO CO LTD (JP) | 1998-02-11 | — | — | CN | disclosed |
| CN-1087812-A | Toiletry composition for hair care | KAO CORP (JP) | 1994-06-15 | — | — | CN | disclosed |
| US-4022792-A | ANALGESICS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3976653-A | ANALGESIC ANTAGONIST | STERLING DRUG INC. (US) | 1976-08-24 | — | — | US | disclosed |